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Product Information:

GSK2334470

GSK2334470 is a highly specific and potent inhibitor of PDK1 with an IC50 of 10 nM.

Cat. No.: EX-A1544    Purity: >98%
GSK2334470
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg400In-stock
250mg785In-stock
500mg1050In-stock
1g1650In-stock
5g5265In-stock
10g8150In-stock


CAS No.1227911-45-6
Purity>98%
FormulaC25H34N8O
Mol Weight462.5905
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Najafov A, et al. Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1. Biochem J.?2011 Jan 15;433(2):357-69.

[2]. Scortegagna M, et al. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma. Oncogene. 2014 Aug 21;33(34):4330-9.

CoACoA of GSK2334470
Smiles:CNC1=NC(=CC(=N1)N1C[C@H](CC[C@H]1C)C(=O)NC1CCCCC1)C1=CC2=C(C=C1)C(N)=NN2

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