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Product Information:

GKT137831

GKT137831 (Setanaxib) is a specific dual NADPH oxidase Nox1/Nox4 inhibitor, respectively. GKT137831 partly inhibits ferroptosis.

Cat. No.: EX-A577    Purity: >98%
GKT137831
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg500In-stock
500mg700In-stock
1g1050In-stock
5g2950In-stock
10g4425In-stock


SynonymsSetanaxib
CAS No.1218942-37-0
Purity>98%
FormulaC21H19ClN4O2
Mol Weight394.854
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Aoyama T, et al. Hepatology. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. 2012, 56(6), 2316-2327.

[2]. Jasmin Dächert, et al. Targeting ferroptosis in rhabdomyosarcoma cells. Int J Cancer. 2020 Jan 15;146(2):510-520.

CoACoA of GKT137831
Smiles:CN(C)C1=CC(=CC=C1)C1=C2C(=O)N(NC2=CC(=O)N1C)C1=CC=CC=C1Cl

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