background


Product Information:

Epacadostat

Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM.

Cat. No.: EX-A793    Purity: >98%
Epacadostat
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg385In-stock
500mg550In-stock
1g850In-stock
5g2285In-stock
10g3585In-stock


SynonymsINCB024360
Synonyms 21204669-37-3
CAS No.1204669-58-8
Purity>98%
FormulaC11H13BrFN7O4S
Mol Weight438.233
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Liu X, et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood. 2010 Apr 29;115(17):3520-30.

[2]. Koblish HK, et al. Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors. Mol Cancer Ther. 2010 Feb;9(2):489-98.

[3]. Fu R, et al. LW106, a novel indoleamine 2,3-dioxygenase 1 inhibitor, suppresses tumour progression by limiting stroma-immune crosstalk and cancer stem cell enrichment in tumour micro-environment. Br J Pharmacol. 2018 Jul;175(14):3034-3049.

CoACoA of Epacadostat
Smiles:NS(=O)(=O)NCCNC1=NONC\1=C(/NC1=CC=C(F)C(Br)=C1)N=O

KEYWORDS: buy Epacadostat | Epacadostat supplier | purchase | cost | manufacturer | order | distributor | buy 1204669-58-8 | 1204669-58-8 supplier