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Product Information:

VX-661

VX-661 (Tezacaftor) is a second corrector of F508 del CFTR.

Cat. No.: EX-A1759    Purity: >98%
VX-661
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg425In-stock
250mg625In-stock
500mg785In-stock
1g1050In-stock
5g3200In-stock
10g4600In-stock


SynonymsTezacaftor
CAS No.1152311-62-0
Purity>98%
FormulaC26H27F3N2O6
Mol Weight520.4976
AppearanceSolid powder
SolubilityDMSO >20mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. S. Donaldson, J. Pilewski, M. Griese, Q. Dong, P.-S. Lee, for the VX11–661-101 Study Group. WS7.3 VX-661, an investigational CFTR corrector, in combination with ivacaftor, a CFTR potentiator, in patients with CF and homozygous for the F508Del-CFTR mutation: Interim analysis. Journal of Cystic Fibrosis, Volume 12, Supplement 1, June 2013, Page S14
CoACoA of VX-661
Smiles:CC(C)(CO)C1=CC2=CC(NC(=O)C3(CC3)C3=CC4=C(OC(F)(F)O4)C=C3)=C(F)C=C2N1C[C@@H](O)CO

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