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Product Information:

EMD-1214063

EMD-1214063 is a potent and selective inhibitor of Met with IC50 value of 4 nM for c-Met.

Cat. No.: EX-A394    Purity: >98%
EMD-1214063
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg565In-stock
1g835In-stock
5g2650In-stock
10g3975In-stock


SynonymsTepotinib
CAS No.1100598-32-0
Purity>98%
FormulaC29H28N6O2
Mol Weight492.5716
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Bladt F, Faden B, Friese-Hamim M, Knuehl C, Wilm C, Fittschen C, Gradler U, Meyring M, Dorsch D, Jaehrling F et al: EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors. Clin Cancer Res, 19(11):2941-2951.

[2]. Bottaro DP, Rubin JS, Faletto DL, Chan AM, Kmiecik TE, Vande Woude GF, Aaronson SA: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991, 251(4995):802-804.
CoACoA of EMD-1214063
Smiles:CN1CCC(COC2=CN=C(N=C2)C2=CC(CN3N=C(C=CC3=O)C3=CC(=CC=C3)C#N)=CC=C2)CC1

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