Ixazomib

Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).


Cat. No.: EX-A547	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	350	In-stock
250mg	485	In-stock
500mg	685	In-stock
1g	885	In-stock
5g	1885	In-stock
10g	2885	In-stock

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Synonyms	MLN-2238
CAS No.	1072833-77-2
Purity	>98%
Formula	C14H19BCl2N2O4
Mol Weight	361.029
Appearance	Solid powder
Solubility	Soluble in DMSO; >50mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kupperman E, et al. Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer. Cancer Res. 2010 Mar 1;70(5):1970-80.
CoA	CoA of Ixazomib

Smiles:	CC(C)C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1Cl)B(O)O


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