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Product Information:

LY2857785

LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).

Cat. No.: EX-A1714    Purity: >98%
Chemical
Chemical structure of LY2857785


For research only, Do not use for Human!

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CAS No.1619903-54-6
Purity>98%
FormulaC26H36N6O
Mol Weight448.6036
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yin T, Lallena MJ, Kreklau EL, et al. A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models. Mol Cancer Ther. 2014;13(6):1442-1456. doi:10.1158/1535-7163.MCT-13-0849

CoACoA of LY2857785
Smiles:CC(C)C1=C2C=C(C=CC2=NN1C)C1=NC(NC2CCC(CC2)NC2CCOCC2)=NC=C1

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