MS049

MS049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells.


Cat. No.: EX-A1395	Purity: >98%

	Chemical structure of MS049

For research only, Do not use for Human!

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CAS No.	1502816-23-0
Purity	>98%
Formula	C15H24N2O
Mol Weight	248.3639
Appearance	white to off-white powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shen Y et al. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6. J Med Chem. 2016 Sep 15.
CoA	CoA of MS049

Smiles:	CNCCN1CCC(CC1)OCC1=CC=CC=C1


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