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Product Information:

ML267

ML 267 is a Novel Pathogenic Sfp phosphopantetheinyl transferase (PPTase) inhibitor.

Cat. No.: EX-A4480    Purity: >98%
ML267
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg485In-stock
10mg785In-stock
25mg1185In-stock
50mg1685In-stock
100mg2685In-stock


SynonymsML-267
Synonyms 2ML 267
CAS No.1542213-67-1
Purity>98%
FormulaC19H18ClF6N5O3S
Mol Weight545.886
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Foley TL, Rai G, Yasgar A, Attene-Ramos MS, Burkart MD, Simeonov A, Jadhav A, Maloney DJ. Discovery of ML 267 as a Novel Inhibitor of Pathogenic Sfp phosphopantetheinyl transferase (PPTase). 2012 Mar 21 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24260781. [2]. Foley TL, Rai G, Yasgar A, Daniel T, Baker HL, Attene-Ramos M, Kosa NM, Leister W, Burkart MD, Jadhav A, Simeonov A, Maloney DJ. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. J Med Chem. 2014 Feb 13;57(3):1063-78. doi: 10.1021/jm401752p. Epub 2014 Jan 22. PMID: 24450337; PMCID: PMC3983359.
CoACoA of ML267

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