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Product Information:

AC1903

AC1903 is a selective inhibitor of TRPC5 with an IC50 value of 14.7 μM.

Cat. No.: EX-A4021    Purity: >98%
AC1903
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg685In-stock
500mg885In-stock
5g2550In-stock


CAS No.831234-13-0
Purity>98%
FormulaC19H17N3O
Mol Weight303.3578
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Y Zhou et al. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science. 2017 Dec 8;358(6368):1332-1336.

[2]. SH Sharma et al. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159.
CoACoA of AC1903
Smiles:C1(NCC2=CC=CO2)=NC3=CC=CC=C3N1CC4=CC=CC=C4

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