CASIN

CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 μM). CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.


Cat. No.: EX-A3979	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	485	In-stock
250mg	585	In-stock
1g	885	In-stock
5g	3250	In-stock
10g	5500	In-stock

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Synonyms	Casin
CAS No.	425399-05-9
Purity	>98%
Formula	C20H22N2O
Mol Weight	306.4015
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Florian et al (2012) Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell 10 520 PMID: 22560076 [2]. Peterson et al (2006) Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components. Chem.Biol. 13 443 PMID: 16632257 [3]. Li et al (2013) Chemical approaches to stem cell biology and therapeutics. Cell Stem Cell 13 270 PMID: 24012368
CoA	CoA of CASIN

Smiles:	OCCNC1C(NC2=C3C=C(C4=CC=CC=C4)C=C2)=C3CCC1


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