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Product Information:

AR231453

AR 231453 is a potent, specific and orally available GPR119 agonist. AR 231453 can stimulate β-cell replication and improve islet graft functions.

Cat. No.: EX-A2992    Purity: >98%
AR231453
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg780In-stock
1g1085In-stock


CAS No.733750-99-7
Purity>98%
FormulaC21H24FN7O5S
Mol Weight505.523
AppearanceSolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chu ZL, et al. A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. Endocrinology. 2007 Jun;148(6):2601-9.

[2]. J Gao, et al. Stimulating β-cell replication and improving islet graft function by AR231453, A GPR119 agonist. Transplant Proc. 2011 Nov;43(9):3217-20.

CoACoA of AR231453
Smiles:CC(C)C1=NOC(=N1)C1CCN(CC1)C1=NC=NC(NC2=CC=C(C=C2F)S(C)(=O)=O)=C1[N+]([O-])=O

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