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Product Information:

AMG-510 racemate

AMG-510 is a specific covalent inhibitor of KRAS G12C with potential antineoplastic activity.

Cat. No.: EX-A3117    Purity: >98%
AMG-510
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg685In-stock
1g1150In-stock
5g3450In-stock
10g5520In-stock


SynonymsAMG510 racemate
Synonyms 2Sotorasib racemate
CAS No.2252403-56-6
Purity>98%
FormulaC31H34F2N6O3
Mol Weight576.6369
Appearancesolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Marwan Fakih, et al, Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and efficacy of AMG 510, a novel small molecule KRASG12Cinhibitor, in advanced solid tumors. Journal of Clinical Oncology.
CoACoA of AMG-510 racemate
Smiles:O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1.[Racemate]

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