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Product Information:

BAY293

BAY-293, a valuable chemical probe, blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM.

Cat. No.: EX-A3181    Purity: >98%
BAY293
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg750In-stock
250mg1185In-stock
1g2500In-stock
2g4200In-stock
5g7685inquire


SynonymsBAY-293
CAS No.2244904-70-7
Purity>98%
FormulaC25H28N4O2S
Mol Weight448.58
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.
CoACoA of BAY293
Smiles:COC1=C(OC)C=C(N=C(C)N=C2N[C@H](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1

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