BAY-218

BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses.


Cat. No.: EX-A3110	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	450	In-stock
200mg	700	In-stock
250mg	750	In-stock
500mg	1000	In-stock
1g	1550	In-stock
5g	4800	In-stock

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Synonyms	BAY 218
CAS No.	2162982-11-6
Purity	>98%
Formula	C20H17ClFN3O3
Mol Weight	401.819
Appearance	Light yellow to yellow solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ilona Gutcher, Christina Kober, Lars Roese,et al.Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor[J].10.1158/1538-7445.AM2019-1288 Published July 2019. [2]. Norbert Schmees, et al. 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides. WO2017202816A1.
CoA	CoA of BAY-218

Smiles:	O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO


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