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Product Information:

ARV-771

ARV-771 is a small-molecule pan-BET degrader.

Cat. No.: EX-A3414    Purity: >98%
ARV-771
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg650In-stock
200mg950In-stock
500mg1550In-stock
1g2450In-stock
2g4000In-stock
5g7800In-stock


CAS No.1949837-12-0
Purity>98%
FormulaC49H60ClN9O7S2
Mol Weight986.64
Appearancesolid powder
SolubilitySoluble in DMSO, >100mg/mL;
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.
CoACoA of ARV-771
Smiles:CC(C(C(C1=CC=C(Cl)C=C1)=N[C@@H](CC(NCCOCCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C2)[C@@H]2C(N[C@H](C3=CC=C(C(SC=N4)=C4C)C=C3)C)=O)=O)=O)=O)C5=NN=C(C)N65)=C6S7)=C7C

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