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Product Information:

A-485

A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively.

Cat. No.: EX-A3090    Purity: >98%
A-485
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg485In-stock
100mg750In-stock
250mg1100In-stock
500mg1800In-stock


CAS No.1889279-16-6
Purity>98%
FormulaC25H24F4N4O5
Mol Weight536.4755
Appearancewhite to off-white powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Lasko LM, et al. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. 2017 Oct 5;550(7674):128-132.
CoACoA of A-485
Smiles:O=C(N1CC(N([C@@H](C)C(F)(F)F)CC2=CC=C(F)C=C2)=O)[C@]3(OC1=O)C4=CC=C(NC(NC)=O)C=C4CC3

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