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Product Information:

CDDO-3P-Im

CDDO-3P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-3P-Im can reduce the size and the severity of the lung tumors in mouse lung cancer model. CDDO-3P-Im is a orally active necroptosis inhibitor that can be used for the research of ischemia/reperfusion (I/R).

Cat. No.: EX-A2715    Purity: >98%
CDDO-3P-Im
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg650In-stock
100mg850In-stock
250mg1250In-stock
500mg1850In-stock
1g2650In-stock
5g6850In-stock


SynonymsCDDO-3P-Imidazolide
CAS No.1883650-95-0
Purity>98%
FormulaC39H46N4O3
Mol Weight618.8075
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cao M , et al. Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention. Pharmacol Res. 2015 Oct;100:135-47.

[2]. Yuanyuan Wang, et al. Discovery of bardoxolone derivatives as novel orally active necroptosis inhibitors. Eur J Med Chem. 2020 Nov 21;113030.

CoACoA of CDDO-3P-Im
Smiles:[H][C@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]3(C)C=C(C#N)C(=O)C(C)(C)C3CC[C@@]12C)C(=O)N1C=NC(=C1)C1=NC=CC=C1

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