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Product Information:

BMS-1166

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM.

Cat. No.: EX-A3096    Purity: >98%
BMS-1166
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg585In-stock
200mg885In-stock
500mg1285In-stock
1g2185In-stock
5g5880In-stock
10g9385In-stock


CAS No.1818314-88-3
Purity>98%
FormulaC36H33ClN2O7
Mol Weight641.109
Appearancewhite to off-white powder
SolubilityDMSO>100mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Guzik K, et al. Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J Med Chem. 2017 Jul 13;60(13):5857-5867.
CoACoA of BMS-1166
Smiles:O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1

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