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Product Information:

ASTX660

ASTX660 is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein (cIAP) and X-linked inhibitor of apoptosis protein (XIAP).

Cat. No.: EX-A2904    Purity: >98%
ASTX660
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg950In-stock
250mg1550In-stock


CAS No.1799328-86-1
Purity>98%
FormulaC30H42FN5O3
Mol Weight539.6846
Appearancewhite to off-white powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Tomoko Smyth, et al. Abstract 1287: The dual IAP antagonist, ASTX660, increases the anti-tumor activity of NSC 125973 in preclinical models of triple-negative breast cancer in vivo. Cancer Res 2016;76(14 Suppl).
CoACoA of ASTX660
Smiles:C[C@@H]1CN(CC(=O)N2CC(C)(C)C3=NC(CO)=C(CC4=CC=C(F)C=C4)C=C23)[C@@H](CN2CCOC[C@H]2C)CN1

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