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Product Information:

ARS-1620

ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Cat. No.: EX-A2836    Purity: >98%
ARS-1620
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg350In-stock
100mg450In-stock
250mg650In-stock
500mg1000In-stock
1g1800In-stock


SynonymsARS-1620 (S enantiomer)
CAS No.1698055-85-4
Purity>98%
FormulaC21H17ClF2N4O2
Mol Weight430.835
Appearanceoff-white to light yellow solid powder
SolubilitySoluble in DMSO/water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Janes MR, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17.

CoACoA of ARS-1620
Smiles:OC1=C(C(F)=CC=C1)C1=C(F)C2=NC=NC(N3CCN(CC3)C(=O)C=C)=C2C=C1Cl

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