background


Product Information:

BMS-986142

BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.

Cat. No.: EX-A2778    Purity: >98%
BMS-986142
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg880In-stock
250mg1450In-stock


CAS No.1643368-58-4
Purity>98%
FormulaC32H30F2N4O4
Mol Weight572.6018
AppearanceSolid powder
SolubilityDMSO >100mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Watterson SH, et al. J Med Chem. 2016 Oct 13;59(19):9173-9200.

2]. Kathleen M. Gillooly, et al. Bruton'styrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care. PLoS One. 2017; 12(7): e0181782.
CoACoA of BMS-986142
Smiles:CN1C(=O)N(C(=O)C2=C1C(F)=CC=C2)C1=CC=CC(=C1C)C1=C(F)C=C(C(N)=O)C2=C1C1=C(C[C@H](CC1)C(C)(C)O)N2

KEYWORDS: buy BMS-986142 | BMS-986142 supplier | purchase | cost | manufacturer | order | distributor | buy 1643368-58-4 | 1643368-58-4 supplier