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Product Information:

A-366

Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. Decreases levels of lysine 9 dimethylation on histone H3 (H3K9Me2) in PC3 cells.

Cat. No.: EX-A2328    Purity: >98%
A-366
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg785In-stock
500mg985In-stock
1g1485In-stock
5gGet quoteIn-stock
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CAS No.1527503-11-2
Purity>98%
FormulaC19H27N3O2
Mol Weight329.4366
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Pappano WN, et al. PLoS One. 2015, 10(7):e0131716.

[2]. Sweis RF, et al. ACS Med Chem Lett. 2014, 5(2):205-209.
CoACoA of A-366
Smiles:COC1=CC2=C(C=C1OCCCN1CCCC1)N=C(N)C21CCC1

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