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Product Information:

ABL001

Asciminib (ABL001) is a potent and selective allosteric Bcr-Abl inhibitor; inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.

Cat. No.: EX-A3030    Purity: >98%
ABL001
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg685In-stock
500mg950In-stock
1g1450In-stock
2g2450In-stock
5g4850In-stock
10g7760In-stock


SynonymsAsciminib
Synonyms 2ABL-001
CAS No.1492952-76-7
Purity>98%
FormulaC20H18ClF2N5O3
Mol Weight449.838
AppearanceOff-white powder
SolubilityDMSO > 100mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Wylie AA, et al. The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1. Nature. 2017 Mar 30;543(7647):733-737.
CoACoA of ABL001
Smiles:O[C@@H]1CCN(C1)C1=C(C=C(C=N1)C(=O)NC1=CC=C(OC(F)(F)Cl)C=C1)C1=NNC=C1

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