Belvarafenib

Belvarafenib (HM95573; RG6185) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.


Cat. No.: EX-A3061	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	600	In-stock
250mg	850	In-stock
1g	1350	In-stock
5g	4950	In-stock
10g	7850	In-stock

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Synonyms	HM95573
Synonyms 2	GDC-5573
CAS No.	1446113-23-0
Purity	>98%
Formula	C23H16ClFN6OS
Mol Weight	478.929
Appearance	white to off-white powder
Solubility	Soluble in DMSO(>10mg/mL), not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. WO 2013/100632 A1.
CoA	CoA of Belvarafenib

Smiles:	CC1=C(C2=C(C=C1)C(=NC=C2)NC3=C(C(=CC=C3)Cl)F)NC(=O)C4=CSC5=C4N=CN=C5N


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