Product Information:
Cat. No.: EX-A2540 | Purity: >98% |
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CAS No. | 1437321-24-8 |
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Purity | >98% |
Formula | C31H26F2N4O6 |
Mol Weight | 588.5581 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1] Erin D. Lew, et al. RXDX-106, a novel, selective and potent small molecule TAM (TYRO3, AXL, MER) inhibitor, demonstrates efficacy in TAM-driven tumors. AACR; Cancer Res 2017, 77(13 Suppl):Abstract nr 4191.
[2]. Sheila M, et al. CEP-40783: A potent and selective AXL/c-Met inhibitor for use in breast, non-small cell lung (NSCLC), and pancreatic cancers. [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2013 Oct 19-23; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2013;12(11 Suppl):Abstract nr C275. |
CoA | CoA of CEP-40783 |
Smiles: | COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4=CN(C(C)C)C(=O)N(C4=O)C4=CC=C(F)C=C4)C=C3F)=CC=NC2=C1 |
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