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Product Information:

AR-13324 hydrochloride

AR-13324 hydrochloride is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.

Cat. No.: EX-A2450    Purity: >98%
AR-13324
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg575In-stock
50mg875In-stock
100mg1275In-stock
200mg1975In-stock


SynonymsNetarsudil dihydrochloride
CAS No.1253952-02-1
Purity>98%
FormulaC28H29Cl2N3O3
Mol Weight526.454
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-54.

[2]. Kiel JW, et al. Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits. J Ocul Pharmacol Ther. 2015 Apr;31(3):146-151.
CoACoA of AR-13324 hydrochloride
Smiles:Cl.Cl.CC1=CC(C)=C(C=C1)C(=O)OCC1=CC=C(C=C1)[C@@H](CN)C(=O)NC1=CC2=C(C=C1)C=NC=C2

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