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Product Information:

BGT226 maleate

BGT226 maleate (NVP-BGT226 maleate) is a PI3K/mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells.

Cat. No.: EX-A3431    Purity: >98%
BGT226
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg400In-stock
250mg750In-stock
500mg1100In-stock
1g1500In-stock


SynonymsNVP-BGT226 maleate
CAS No.1245537-68-1
Purity>98%
FormulaC32H29F3N6O6
Mol Weight650.6045
Appearancesolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Markman B, et al. Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors. Ann Oncol. 2012 Sep;23(9):2399-408.

[2]. Chang KY, et al. Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo. Clin Cancer Res. 2011 Nov 15;17(22):7116-26.
CoACoA of BGT226 maleate
Smiles:COC1=CC=C(C=N1)C2=CC=C(C3=C2)N=CC(N4C)=C3N(C4=O)C5=CC=C(C(C(F)(F)F)=C5)N6CCNCC6.OC(/C=C\C(O)=O)=O

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