Synonyms | NVP-BGT226 maleate |
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CAS No. | 1245537-68-1 |
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Purity | >98% |
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Formula | C32H29F3N6O6 |
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Mol Weight | 650.6045 |
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Appearance | solid powder |
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Solubility | Soluble in DMSO, not in water |
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Shelf Life | >2 years if stored properly |
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Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
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Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Reference: | [1]. Markman B, et al. Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors. Ann Oncol. 2012 Sep;23(9):2399-408.
[2]. Chang KY, et al. Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo. Clin Cancer Res. 2011 Nov 15;17(22):7116-26. |
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CoA | CoA of BGT226 maleate |
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