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Product Information:

Acrizanib

Acrizanib is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-KDR.

Cat. No.: EX-A3028    Purity: >98%
Acrizanib
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg685In-stock
100mg895In-stock
250mg1450In-stock
500mg2000In-stock
1g3000In-stock


CAS No.1229453-99-9
Purity>98%
FormulaC20H18F3N7O2
Mol Weight445.3978
AppearancePowder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Adams CM, et al. The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration. J Med Chem. 2018 Feb 22;61(4):1622-1635.
CoACoA of Acrizanib
Smiles:CNCC1=CC(OC2=CC=C3N(C=CC3=C2)C(=O)NC2=NN(C)C(=C2)C(F)(F)F)=NC=N1

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