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Product Information:

CXD101

CXD101 is a potent class 1 selective HDAC inhibitor with IC50s of 63 nM, 570 nM, 550 nM for HDAC1, HDAC2, and HDAC3, respectively. CXD101 has no activity against class 2 HDAC. CXD101 demonstrates potent antiproliferative activity against various cancer cells in vitro.

Cat. No.: EX-A1143    Purity: >98%
CXD101
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg585In-stock
200mg985In-stock
500mg1350In-stock


SynonymsHDAC-IN-4
CAS No.934828-12-3
Purity>98%
FormulaC24H29N5O
Mol Weight403.52
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Eyre TA, et al. Predictive biomarkers for disease sensitivity in lymphoma - the holy grail for HDAC inhibitors? Oncotarget. 2018 Dec 18;9(99):37280-37281.

[2]. Eyre TA, et al. A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer. Cancer. 2019 Jan 1;125(1):99-108.
CoACoA of CXD101
Smiles:CN1C=C(CN2CCC(CC2)C2=CC=C(C=C2)C(=O)NC2=CC=CC=C2N)C(C)=N1

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