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Product Information:

AdipoRon

AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.

Cat. No.: EX-A283    Purity: >98%
AdipoRon
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg300In-stock
250mg450In-stock
500mg600In-stock
1g850In-stock
5g2650In-stock
10g3800inquire


SynonymsSC-396658
CAS No.924416-43-3
Purity>98%
FormulaC27H28N2O3
Mol Weight428.5228
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Okada-Iwabu M, et al. A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature. 2013 Nov 28;503(7477):493-9.

[2]. Wang Y, et al. Hepatoprotective effects of AdipoRon against d-galactosamine-induced liver injury in mice. Eur J Pharm Sci. 2016 Aug 9;93:123-131.

[3]. Zhang Y, et al. AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings. Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E275-82.

[4]. Hong K, et al. Adiponectin Receptor Agonist, AdipoRon, Causes Vasorelaxation Predominantly Via a Direct Smooth Muscle Action. Microcirculation. 2016 Apr;23(3):207-20.

CoACoA of AdipoRon
Smiles:O=C(COC1=CC=C(C=C1)C(=O)C1=CC=CC=C1)NC1CCN(CC2=CC=CC=C2)CC1

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