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Product Information:

ARRY-520

Filanesib (ARRY-520) is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity.

Cat. No.: EX-A678    Purity: >98%
ARRY-520
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg685In-stock
100mg985In-stock
250mg1585In-stock
1g3585In-stock
5g13500inquire
10g22250inquire


SynonymsFilanesib
CAS No.885060-09-3
Purity>98%
FormulaC20H22F2N4O2S
Mol Weight420.476
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Woessner, R., Tunquist, B., Lemieux, C., et al. ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models. Anticancer Res. 29(11), 4373-4380 (2009).

[2]. Carter, B.Z., Mak, D.H., Woessner, R., et al. Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells. Leukemia 23(10), 1755-1762 (2009).
CoACoA of ARRY-520
Smiles:CON(C)C(=O)N1N=C(S[C@@]1(CCCN)C1=CC=CC=C1)C1=CC(F)=CC=C1F

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