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Product Information:

Bentamapimod

Bentamapimod (AS 602801) is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.

Cat. No.: EX-A1361    Purity: >98%
Bentamapimod
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg890In-stock
1g1650In-stock


SynonymsAS 602801
CAS No.848344-36-5
Purity>98%
FormulaC25H23N5O2S
Mol Weight457.547
AppearanceSolid powder
SolubilityDMSO >10 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Messoussi A, et al. Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticanceragents. Chem Biol. 2014 Nov 20;21(11):1433-43.

[2]. Okada M, et al. The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo. Oncotarget. 2016 May 10;7(19):27021-32.

[3]. Palmer SS, et al. Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models. Reprod Sci. 2016 Jan;23(1):11-23.
CoACoA of Bentamapimod
Smiles:N#CC(C1=NC2=CC=CC=C2S1)C1=NC(OCC2=CC=C(CN3CCOCC3)C=C2)=NC=C1

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