4'-Demethylepipodophyllotoxin

4'-Demethylepipodophyllotoxin(4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly. IC50 Value: 0.31uM(EC5 0in HL60 cell, MTT assay, 48h);


Cat. No.: EX-A1205	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	185	In-stock
5g	550	In-stock
10g	800	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


Synonyms	4'-O-demethylepipodophyllotoxin
Synonyms 2	4'-DMEP
CAS No.	6559-91-7
Purity	>98%
Formula	C21H20O8
Mol Weight	400.3787
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tang YJ, Zhao W, Li HM. Novel tandem biotransformation process for the biosynthesis of a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4'-demethylepipodophyllotoxin. Appl Environ Microbiol. 2011 May;77(9):3023-34. [2]. Dhawan D, Balasubramanian S, Amonkar AJ, Chemopreventive effect of 4'-demethyl epipodophyllotoxin on DMBA/TPA-induced mouse skin carcinogenesis. Carcinogenesis. 1999 Jun;20(6):997-1003.
CoA	CoA of 4'-Demethylepipodophyllotoxin

Smiles:	[H][C@]12COC(=O)[C@]1([H])[C@H](C1=CC(OC)=C(O)C(OC)=C1)C1=C(C=C3OCOC3=C1)[C@H]2O


		Search