CPI-360

CPI-360 is a small molecule EZH2 inhibitor (IC50: 0.002 μM, EC50: 0.080 μM) that shows antitumor activity in an EZH200-dependent tumor xenograft model.


Cat. No.: EX-A676	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	550	In-stock
100mg	750	In-stock
250mg	1150	In-stock
500mg	1650	In-stock
1g	2450	In-stock
5g	7350	In-stock

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CAS No.	1802175-06-9
Purity	>98%
Formula	C25H31N3O4
Mol Weight	437.5313
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Vatolin S, et al. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma. Cancer Res. 2016 Jun 1;76(11):3340-50. [2]. Felder ChB, et al. Ultrasonic atomization and subsequent polymer desolvation for peptide and protein microencapsulation into biodegradable polyesters. J Microencapsul. 2003;20(5):553-567. [3]. Lang S, et al. Transport and metabolic pathway of thymocartin (TP4) in excised bovine nasal mucosa. J Pharm Pharmacol. 1996;48(11):1190-1196. [4]. Arora S, et al. EZH2 inhibitors are broadly efficacious in multiple myeloma as single agent and in combination with standard of care therapeutics. 2016.
CoA	CoA of CPI-360

Smiles:	COC1=C(CNC(=O)C2=C(C)N([C@H](C)C3CCOCC3)C3=C2C=CC=C3)C(=O)NC(C)=C1


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