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Product Information:

BLU-9931

BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity.

Cat. No.: EX-A608    Purity: >98%
BLU-9931
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg450In-stock
500mg785In-stock
1g1150In-stock
5g3450In-stock
10g5500In-stock


CAS No.1538604-68-0
Purity>98%
FormulaC26H22Cl2N4O3
Mol Weight509.384
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hagel M, et al. First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. Cancer Discov. 2015 Apr;5(4):424-37.

CoACoA of BLU-9931
Smiles:COC1=CC(OC)=C(Cl)C(C2=CC3=CN=C(NC4=C(C)C=CC=C4NC(=O)C=C)N=C3C=C2)=C1Cl

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