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Product Information:

ACY-1215

Ricolinostat (ACY-1215) is a potent and selective HDAC6 inhibitor, with an IC50 of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 58, 48, and 51 nM, respectively.

Cat. No.: EX-A139    Purity: >98%
ACY-1215
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg175Inquire
250mg250Inquire
500mg400In-stock
1g635In-stock
5g1585In-stock
10g2885In-stock


SynonymsRicolinostat
Synonyms 2Rocilinostat
CAS No.1316214-52-4
Purity>98%
FormulaC24H28ClN5O3
Mol Weight469.964
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Santo L, et al. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with PS-341 in multiple myeloma. Blood. 2012 Mar 15;119(11):2579-89.

CoACoA of ACY-1215
Smiles:Cl.ONC(=O)CCCCCCNC(=O)C1=CN=C(N=C1)N(C1=CC=CC=C1)C1=CC=CC=C1

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