ABT-199

Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1.


Cat. No.: EX-A168	Purity: >99%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	585	In-stock
1g	785	In-stock
5g	1785	In-stock
10g	2985	In-stock

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Synonyms	Venetoclax
CAS No.	1257044-40-8
Purity	>99%
Formula	C45H50ClN7O7S
Mol Weight	868.439
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Souers AJ, et al. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. Nat Med, 2013, 19(2), 202-208.
CoA	CoA of ABT-199

Smiles:	CC1(C)CCC(CN2CCN(CC2)C2=CC=C(C(=O)NS(=O)(=O)C3=CC=C(NCC4CCOCC4)C(=C3)[N+]([O-])=O)C(OC3=CN=C4NC=CC4=C3)=C2)=C(C1)C1=CC=C(Cl)C=C1


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