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Product Information:

A-1155463

A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.

Cat. No.: EX-A1060    Purity: >98%
A-1155463
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg685In-stock
250mg1350In-stock
1g2950In-stock
5gGet quoteIn-stock
10gGet quoteinquire


CAS No.1235034-55-5
Purity>98%
FormulaC35H32FN5O4S2
Mol Weight669.788
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Tao ZF, et al. Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity. ACS Med Chem Lett. 2014 Aug 26;5(10):1088-93.

[2]. Zhang H, et al. Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer. Mol Cancer. 2015 Jul 2;14:126.

CoACoA of A-1155463
Smiles:CN(C)CC#CC1=CC=C(OCCCC2=C(N=C(S2)N2CCC3=C(C2)C(=CC=C3)C(=O)NC2=NC3=CC=CC=C3S2)C(O)=O)C(F)=C1

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