BI-847325

BI-847325 is an ATP competitive dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively. BI-847325 is a click chemistry reagent.


Cat. No.: EX-A1727	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	650	In-stock
500mg	850	In-stock
1g	1350	In-stock
5g	4850	In-stock

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CAS No.	1207293-36-4
Purity	>98%
Formula	C29H28N4O2
Mol Weight	464.5582
Appearance	Light yellow to yellow solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sini P, et al. Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases. Mol Cancer Ther. 2016 Oct;15(10):2388-2398.
CoA	CoA of BI-847325

Smiles:	CCNC(=O)C#CC1=CC2=C(C=C1)\C(C(=O)N2)=C(\NC1=CC=C(CN(C)C)C=C1)C1=CC=CC=C1


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