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Product Information:

APD334

Etrasimod is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).

Cat. No.: EX-A1633    Purity: >98%
APD334
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg550In-stock
250mg885In-stock
500mg1285In-stock
1g1985In-stock
5g6500In-stock
10g9500In-stock


SynonymsEtrasimod
CAS No.1206123-37-6
Purity>98%
FormulaC26H26F3NO3
Mol Weight457.4847
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Buzard, Daniel J et al. Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor. ACS medicinal chemistry letters vol. 5,12 1313-7. 4 Nov. 2014.

CoACoA of APD334
Smiles:OC(=O)C[C@H]1CCC2=C1NC1=CC=C(OCC3=CC=C(C4CCCC4)C(=C3)C(F)(F)F)C=C21

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