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Product Information:

AZD5363

AZD5363 (Capivasertib) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).

Cat. No.: EX-A285    Purity: >98%
AZD5363
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg650In-stock
500mg850In-stock
1g1175In-stock
5g4800In-stock
10g8500In-stock


SynonymsCapivasertib
CAS No.1143532-39-1
Purity>98%
FormulaC21H25ClN6O2
Mol Weight428.915
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Davies BR, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Mol Cancer Ther. 2012 Apr;11(4):873-87.
CoACoA of AZD5363
Smiles:NC1(CCN(CC1)C1=C2C=CNC2=NC=N1)C(=O)N[C@@H](CCO)C1=CC=C(Cl)C=C1

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