background


Product Information:

CX-4945

CX-4945 is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'.

Cat. No.: EX-A070    Purity: >99%
CX-4945
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1g460In-stock
5g1550In-stock


SynonymsSilmitasertib
CAS No.1009820-21-6
Purity>99%
FormulaC19H12ClN3O2
Mol Weight349.77
Appearancewhite to off-white powder
SolubilityDMSO >30mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Siddiqui-Jain A, et al. CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy. Cancer Res. 2010 Dec 15;70(24):10288-98.

[2]. Buontempo F, et al. Synergistic cytotoxic effects of PS-341 and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB. Oncotarget. 2016 Jan 12;7(2):1323-40.
CoACoA of CX-4945
Smiles:OC(=O)C1=CC=C2C(=C1)N=C(NC1=CC=CC(Cl)=C1)C1=C2C=NC=C1

KEYWORDS: buy CX-4945 | CX-4945 supplier | purchase | cost | manufacturer | order | distributor | buy 1009820-21-6 | 1009820-21-6 supplier